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Liver

Conditions Hub

Common Liver, Pancreas, Bile Duct and Gallbladder Conditions

Specialist information on conditions affecting the liver, pancreas, bile ducts and gallbladder — including liver disease, liver cancer, pancreatic conditions, gallstones, bile duct obstruction and complex HPB conditions that may need surgical or transplant assessment.

This page provides general information only and does not replace an individual medical assessment, diagnosis or treatment plan.

Quick answer

When should you see a liver or HPB specialist?

You may need specialist liver or HPB assessment if you have abnormal liver tests, jaundice, a liver or pancreatic scan finding, suspected liver cancer, complicated gallstones, bile duct obstruction, cirrhosis, advanced liver disease, or if you have been advised to consider liver surgery, pancreatic surgery, bile duct surgery or liver transplant assessment.

Abnormal liver testsJaundiceLiver tumourPancreatic cystGallstonesBile duct obstructionTransplant assessment
Start with what you are concerned about

Common liver and HPB conditions

Conditions in this area can be first noticed through symptoms, blood tests, ultrasound, CT, MRI, MRCP or other investigations. Some conditions are managed with monitoring or medicine, while others may need specialist surgical, oncological, endoscopic or transplant review.

Liver Conditions

The liver can be affected by metabolic, viral, alcohol-related, autoimmune, inherited, bile duct-related and cancerous conditions.

  • Fatty liver disease / steatotic liver disease
  • Liver cirrhosis and fibrosis
  • Hepatitis B and hepatitis C
  • Alcohol-related liver disease
  • Autoimmune liver conditions
  • Liver failure
  • Liver cysts and benign liver lesions
Explore liver health →

Liver Cancer and Liver Tumours

Liver cancer may begin in the liver or spread to the liver from another part of the body. Treatment depends on tumour type, stage, location, liver function and overall health.

  • Hepatocellular carcinoma, also called HCC
  • Cholangiocarcinoma / bile duct cancer
  • Secondary liver cancer / liver metastases
  • Colorectal liver metastases
  • Complex liver lesions
  • Liver tumours in patients with cirrhosis
Explore liver cancer treatment →

Pancreatic Conditions

Pancreatic conditions may involve inflammation, cysts, tumours or cancer. Some are found because of abdominal pain, jaundice, weight loss or abnormal scan findings.

  • Pancreatic cancer
  • Pancreatic cysts
  • IPMN and mucinous cystic neoplasms
  • Acute pancreatitis
  • Chronic pancreatitis
  • Pancreatic neuroendocrine tumours
  • Whipple procedure or distal pancreatectomy assessment
Explore pancreatic surgery →

Gallbladder and Bile Duct Conditions

Gallbladder and bile duct conditions are common reasons for upper abdominal pain, jaundice and abnormal liver blood tests.

  • Gallstones
  • Recurrent biliary colic
  • Acute cholecystitis
  • Common bile duct stones
  • Bile duct obstruction
  • Bile duct strictures
  • Gallbladder cancer or bile duct cancer
Explore gallbladder and bile duct care →
Symptoms that need attention

When should liver, bile duct or pancreatic symptoms be checked?

Symptoms can appear in different ways. Some are mild or vague, while others may suggest bile duct obstruction, infection, advanced liver disease or another condition that needs prompt assessment.

Seek prompt medical advice if you notice yellowing of the eyes or skin, dark urine, pale stools, severe itching, unexplained weight loss, ongoing vomiting, fever with abdominal pain or jaundice, swelling of the abdomen or legs, confusion, vomiting blood or passing black stools.

Patient pathway illustration
Assessment

How are liver and HPB conditions assessed?

A specialist consultation usually begins with your symptoms, history, previous reports and scan findings. Complex cases may require coordinated review by more than one specialist.

01

Review symptoms and history

Your doctor reviews symptoms, medical background, medicines, previous treatment and risk factors.

02

Check blood tests

Blood tests may include liver function tests, infection markers, clotting tests or tumour markers.

03

Review imaging

Ultrasound, CT, MRI, MRCP, PET or other imaging may be reviewed depending on the diagnosis.

04

Clarify diagnosis

Further tests, endoscopy, biopsy or pathology review may be recommended when needed.

05

Discuss treatment options

Options may include monitoring, medicines, endoscopy, radiology, oncology care, surgery or transplant assessment.

06

Plan next steps

The consultation should explain the likely pathway, risks, alternatives, preparation and follow-up.

Treatment planning

Treatment depends on the individual patient

The same diagnosis can require different treatment in different patients. For example, treatment for liver cancer may depend on tumour size and location, liver function, cancer stage, cirrhosis, general health and whether surgery is safe.

Treatment may include monitoring, medicines, endoscopic procedures, interventional radiology, oncology treatment, liver resection, pancreatic surgery, bile duct surgery, gallbladder surgery or liver transplant assessment in selected cases.

Prepare for your consultation

What should you bring?

  • Recent blood test results
  • Liver function tests
  • Ultrasound, CT, MRI or MRCP reports
  • Scan images on CD, USB or link
  • Biopsy or pathology reports
  • Endoscopy or ERCP reports
  • Discharge summaries
  • Current medicines and supplements
  • Previous surgery or cancer treatment records
  • A short timeline of symptoms and diagnosis
Frequently asked questions

Questions about liver and HPB conditions

What is an HPB surgeon?

An HPB surgeon is a hepatobiliary-pancreatic surgeon who specialises in complex conditions and surgery involving the liver, pancreas, bile ducts and gallbladder.

Do abnormal liver tests always mean serious liver disease?

No. Abnormal liver tests can have many causes and should be interpreted together with symptoms, medical history, medicines, risk factors and imaging.

Can liver disease be present without symptoms?

Yes. Some liver conditions cause few or no symptoms in the early stages and are first found through routine blood tests or scans.

When is liver surgery considered?

Liver surgery may be considered for selected liver tumours, liver cancer, secondary liver tumours, some benign liver lesions and other complex liver conditions.

When is liver transplant assessment considered?

Liver transplant assessment may be considered for selected patients with advanced liver disease, acute liver failure or certain liver cancers after detailed evaluation by a transplant team.

Are all gallstones treated with surgery?

No. Some gallstones do not cause symptoms and may not need surgery. Surgery may be considered when gallstones cause pain, infection, inflammation or bile duct blockage.

Can pancreatic cysts become cancer?

Some pancreatic cysts have a higher risk than others. Specialist review helps determine whether monitoring, further testing or surgery should be considered.

Can I request a second opinion?

Yes. Patients may request specialist review for a new diagnosis, abnormal scan, liver cancer, pancreatic condition, gallbladder or bile duct condition, transplant assessment or complex HPB surgery recommendation.

Need a specialist opinion?

Book a liver and HPB specialist consultation in Colombo

Request a consultation with Prof. Thamara Perera at Kings Hospital Colombo for liver disease, liver cancer, pancreatic conditions, gallbladder disease, bile duct obstruction, liver transplant assessment or a second opinion on complex HPB surgery.