Confirm the diagnosis
The team reviews symptoms, examination findings, blood tests, scans and previous medical records. Further tests are arranged only when they are needed.
Clear information on liver transplantation, liver resection, hepatobiliary surgery, pancreatic surgery, bile duct surgery, gallbladder surgery and minimally invasive approaches. Treatment is planned around the diagnosis, imaging findings, liver function and overall health.
This page provides general information. The appropriate treatment can only be decided after an individual clinical assessment and review of relevant tests.
HPB surgery means hepatobiliary-pancreatic surgery. It covers operations involving the liver, bile ducts, gallbladder and pancreas. Depending on the condition, treatment may include removing diseased tissue, reconstructing a bile duct, removing the gallbladder, pancreatic surgery or liver transplantation.
Not every HPB condition requires surgery. Some patients are monitored or treated with medicines, endoscopy, interventional radiology, oncology treatment or a combination of approaches.
Each treatment page explains what the procedure is, why it may be considered, how patients are assessed, what the operation may involve and how follow-up is planned.

A diseased or injured liver is removed and replaced with a healthy liver from a donor. Transplantation may be considered for selected patients with advanced liver failure, acute liver failure or certain liver cancers.
Understand liver transplantation →
Part of a healthy donor's liver is transplanted into the recipient. Donor and recipient assessments are separate and detailed because the operation involves clinical considerations for both people.
Learn about LDLT surgery →
Liver resection, also called hepatectomy, removes the part of the liver containing a tumour or another area of disease while preserving an adequate functioning liver remnant.
Understand hepatectomy →
HPB surgery includes planned operations for complex conditions of the liver, pancreas, bile ducts and gallbladder. The exact procedure depends on the organ involved and the diagnosis.
Explore HPB surgery →

Pancreatic surgery may include a Whipple procedure, distal pancreatectomy or total pancreatectomy. The operation is selected according to the location and type of pancreatic condition.
Pancreatic and Whipple surgery →
Cholecystectomy is surgery to remove the gallbladder. It is commonly performed using a laparoscopic approach, although an open operation may be needed in some situations.
Understand cholecystectomy →
Biliary surgery may remove, repair or reconstruct part of the bile duct. Depending on the location of disease, it may be combined with liver, gallbladder or pancreatic surgery.
Explore biliary surgery →
Selected procedures may be performed using laparoscopic or robotic techniques through smaller incisions. Suitability depends on the operation, anatomy, disease extent and available expertise.
Laparoscopic and robotic approaches →The same diagnosis can require different treatment in different people. Decisions are based on the location and extent of disease, liver and organ function, previous treatment, general health and the likely benefits and risks of each option.
Imaging is interpreted together with symptoms, blood tests, medical history and, where relevant, pathology or biopsy findings.
The team reviews symptoms, examination findings, blood tests, scans and previous medical records. Further tests are arranged only when they are needed.
Ultrasound, CT, MRI, endoscopy or other investigations may be used to understand where the condition is and how it relates to nearby blood vessels, bile ducts and organs.
Planning considers how well the liver and other organs are working, existing health conditions, medicines, nutrition and the ability to recover from treatment.
Complex cases may be discussed by surgeons, physicians, radiologists, oncologists, anaesthetists, pathologists and other specialists before a recommendation is made.
The consultation should cover the purpose of treatment, alternatives, expected recovery, possible risks and what follow-up may be required.
This hub focuses on liver surgery and HPB surgery in Sri Lanka, but surgery is only one part of care. Depending on the diagnosis, a patient may need medical treatment, endoscopic procedures, interventional radiology, oncology treatment, surgery or planned combinations of these.
Medicines, monitoring and management of underlying liver, metabolic or inflammatory conditions may be the main treatment or may support surgical care.
Endoscopic procedures may be used to assess or treat bile duct obstruction, stones, narrowing or drainage problems in selected cases.
Image-guided drainage, biopsy, ablation or treatments delivered through blood vessels may be considered for particular conditions.
Chemotherapy, targeted therapy, immunotherapy or radiotherapy may be used before surgery, after surgery or instead of surgery, depending on the cancer type and stage.
The surgical approach is selected according to the planned procedure and the patient's clinical needs. Smaller incisions do not automatically make an operation more suitable; safety and the ability to complete the required treatment remain central.
An open incision provides direct access and may be needed for extensive resections, transplantation, reconstruction or operations involving complex anatomy.
Laparoscopic surgery uses a camera and instruments placed through small incisions. Selected gallbladder, liver and other HPB operations may be suitable for this approach.
Robotic surgery uses surgeon-controlled instruments and a magnified view. Patients considering robotic liver surgery in Sri Lanka should ask whether the approach is suitable and available for their specific operation.
Yes. A surgeon may recommend or convert to an open approach when this is needed to complete the operation safely. The possibility should be discussed during consent.
Preparation and recovery vary according to the procedure. Your surgical team will provide instructions based on your health, medicines, operation and expected hospital stay.
Blood tests, imaging, heart or lung assessment and anaesthetic review may be arranged according to the procedure and your health history.
Tell the team about all prescription medicines, blood thinners, supplements and herbal products. Do not stop medicines unless your clinician advises you to.
Care may include pain control, early movement, breathing exercises, nutrition support and monitoring for procedure-specific complications.
Follow-up may include wound review, blood tests, pathology results, imaging, medication changes and coordination with other specialists.
Prof. Thamara Perera is an internationally experienced and extensively published surgeon specialising in liver transplantation, liver cancer and complex surgery of the liver, pancreas, bile ducts and gallbladder.
Patients may seek a consultation after a diagnosis, an abnormal scan, a recommendation for surgery, or when they need a specialist opinion on available treatment options.
View Prof. Perera's ProfileHPB surgery means hepatobiliary-pancreatic surgery. It is a surgical specialty focused on conditions affecting the liver, pancreas, bile ducts and gallbladder. Operations may include resection, reconstruction, transplantation or minimally invasive procedures.
Liver resection, also called hepatectomy, removes part of the liver containing a tumour or another area of disease. The planned resection depends on the location and extent of disease and on how much functioning liver can safely remain.
Liver transplantation may be considered for selected people with advanced liver failure, sudden severe liver failure or certain liver cancers. A transplant assessment considers the likely benefits, medical and surgical risks, psychosocial factors and donor options.
A living donor liver transplant uses part of the liver from a healthy living donor. The recipient's diseased liver is removed and the donated liver segment is transplanted. The donor and recipient require detailed, separate assessments and follow-up.
The Whipple procedure, or pancreaticoduodenectomy, removes the head of the pancreas together with nearby structures and then reconnects the digestive system. It may be used for selected conditions affecting the pancreas, lower bile duct, duodenum or ampulla.
Gallbladder removal, or cholecystectomy, is commonly performed laparoscopically through small incisions. An open operation may be required because of inflammation, scar tissue, anatomy, unexpected findings or another clinical reason.
Some liver resections and other HPB procedures can be performed laparoscopically or robotically. Suitability depends on the type and position of disease, planned extent of surgery, previous operations, available technology and the experience of the surgical team.
You can book a consultation at Kings Hospital Colombo through the Liver.lk appointment page. Bring available scan reports, blood-test results, pathology reports, discharge summaries and a current medicine list to help the specialist review your case.
Book a consultation for a diagnosed liver, pancreatic, bile duct or gallbladder condition, an abnormal scan, a proposed operation or a second opinion at Kings Hospital Colombo.