Tiredness and reduced appetite
Persistent fatigue, low energy, reduced appetite, nausea or unplanned weight loss may occur in liver disease, but they are not specific to the liver.
A clear guide to liver disease symptoms, common liver conditions and the next steps for assessment. Liver.lk provides patient-friendly information and pathways to specialist care for liver disease in Sri Lanka.
This page provides general information and does not replace an individual medical assessment. Symptoms alone cannot confirm liver disease.
Possible symptoms include ongoing tiredness, reduced appetite, nausea, discomfort beneath the right ribs, itching, yellowing of the eyes or skin, dark urine, pale stools, easy bruising and swelling of the abdomen or legs.
Important: these symptoms can be caused by many different conditions. A doctor may use your history, examination and appropriate tests to identify the cause.
Some symptoms are general, while others are more closely associated with changes in how the liver or bile ducts are working. The pattern, duration and combination of symptoms matter more than any one symptom on its own.
Persistent fatigue, low energy, reduced appetite, nausea or unplanned weight loss may occur in liver disease, but they are not specific to the liver.
Some people feel mild pain, pressure or discomfort in the upper right abdomen. This area also contains the gallbladder and nearby organs, so assessment is needed.
Jaundice occurs when bilirubin builds up in the body. It may be linked to liver disease, bile duct blockage, blood conditions or other causes.
Dark urine and unusually pale stools can occur when bile flow is affected. Temporary colour changes may also have other explanations.
Ongoing itching, bruising more easily than usual or prolonged bleeding may occur when liver or bile-related conditions affect normal body processes.
Swelling of the abdomen, ankles or legs, or new confusion and unusual drowsiness, should be assessed promptly.
Yes. Several liver conditions may cause few or no noticeable symptoms early and may first be found through blood tests or imaging performed for another reason. People with risk factors or abnormal test results may need further assessment even when they feel well.
A calm, timely assessment can help clarify whether symptoms are liver-related and whether any tests or specialist referral are needed.
Tap an icon below to see causes, symptoms, assessment and treatment for each condition.

Fat buildup in the liver, now often described as steatotic liver disease. It is frequently associated with metabolic health.
Fatty liver symptoms and care →
Long-term scarring that changes the structure of the liver and may affect how it works.
Cirrhosis symptoms and treatment →
Cancers that begin in the liver or spread to it from another part of the body require different treatment pathways.
Liver cancer information →
Inflammation of the liver that may be caused by viruses, medicines, alcohol, autoimmune disease or other conditions.
Hepatitis symptoms and testing →
A serious reduction in liver function that may develop quickly or occur after long-term liver disease.
Causes and symptoms →
Yellowing of the eyes or skin caused by increased bilirubin. It is a sign that needs assessment, not a diagnosis by itself.
Understand jaundice causes →

Gallstones and inflammation can cause upper abdominal pain, nausea or problems with bile flow.
Gallstone symptoms →
Narrowing, blockage, stones or inflammation in the bile ducts can affect drainage of bile from the liver.
Bile duct obstruction →
Pancreatitis, cysts and pancreatic tumours may share symptoms with liver and bile duct conditions.
Pancreatitis symptoms →
Fluid-filled spaces in the liver are often found during imaging. Their significance depends on the type and features.
Liver cyst assessment →
A collection of infection within the liver that usually requires medical treatment and, in some cases, drainage.
Symptoms and treatment →
Non-cancerous conditions include haemangiomas, focal nodular hyperplasia and some liver adenomas.
Benign liver conditions →Liver disease is not one condition. It includes metabolic, infectious, alcohol-related, autoimmune, inherited, medicine-related and bile duct disorders. More than one factor can be present at the same time.
Read Liver Health GuidesOverweight, type 2 diabetes, high cholesterol and other metabolic factors are associated with fatty or steatotic liver disease.
Hepatitis viruses can inflame the liver. Hepatitis B and C can become chronic, while prevention and treatment options depend on the virus.
Alcohol affects people differently. The risk of liver injury depends on the amount, pattern of use, duration and individual health factors.
Some prescription medicines, non-prescription medicines, herbal products and supplements can cause liver injury in certain circumstances.
The immune system or inherited changes can affect liver cells, bile ducts or the way the body processes substances such as copper or iron.
Gallstones, narrowing, inflammation, tumours or previous surgery can interfere with bile drainage and affect the liver.
There is no single test for every liver condition. The assessment is chosen according to your symptoms, medical history, examination and previous results.
Your doctor may ask about symptoms, medicines and supplements, alcohol use, metabolic conditions, family history, previous infections and earlier test results.
Blood tests may look for liver inflammation or injury, bile flow problems, infections, blood clotting and how well the liver is carrying out some of its functions.
Ultrasound, CT or MRI may be used to examine the liver, gallbladder, bile ducts, pancreas and blood vessels, depending on the clinical question.
Elastography is a non-invasive test that estimates liver stiffness and may help assess fibrosis or scarring.
A small tissue sample may be recommended when blood tests and imaging do not provide enough information, or when the type or severity of disease needs clarification.
General health measures can support liver health, but people with a diagnosed condition should follow advice tailored to their individual needs.
Many liver conditions are managed medically by gastroenterologists or hepatologists. A hepatobiliary-pancreatic surgeon, also called an HPB surgeon, assesses liver, bile duct, gallbladder and pancreatic conditions that may require surgery, as well as liver transplantation.
Book a Specialist ConsultationPossible symptoms include ongoing tiredness, reduced appetite, nausea, discomfort beneath the right ribs, itching, jaundice, dark urine, pale stools, easy bruising and swelling of the abdomen or legs. These symptoms are not specific to liver disease and should be interpreted alongside an examination and tests.
Yes. Some conditions cause few or no noticeable symptoms early and may first be identified through abnormal blood tests or an ultrasound or scan performed for another reason.
Liver-related discomfort may be felt in the upper right abdomen beneath the ribs. Pain in this area may also come from the gallbladder, stomach, muscles, lungs or other organs, so location alone cannot identify the cause.
No. Abnormal results can have several explanations and need to be interpreted in context. Your doctor may repeat tests, review medicines and health conditions, or arrange imaging or specialist assessment.
Depending on the situation, assessment may include liver blood tests, viral hepatitis tests, ultrasound, CT, MRI, elastography and, less commonly, liver biopsy.
An HPB surgeon may be involved when a condition affects the liver, bile ducts, gallbladder or pancreas and surgery may be part of treatment. This includes liver tumours, bile duct obstruction, pancreatic disease, gallbladder surgery and liver transplantation.
Book a consultation for persistent liver disease symptoms, an abnormal test result, a diagnosed liver condition or a specialist surgical opinion at Kings Hospital Colombo.